What does triple-negative breast cancer mean?

Cancer especially breast Cancer is a disease where cells in the breast grow out of control. It is the most common type of cancer in women all over the world. Though deaths from breast cancer have declined it remains the second leading cause of cancer-related death among women. Triple-negative breast cancer or TNBC is a very uncommon kind of breast cancer as it does not have any receptors that are usually found in other types of breast cancer.

Though triple-negative breast cancers are sometimes challenging to treat, Dr. Manish Singhal, an Oncologist in Noida and specialized in cancer treatment explains that triple-negative breast cancer can be curable which gives patients reasons for hope. Triple-negative breast cancer is common in patients with hereditary genetic mutations. A renowned Cancer Doctor in Noida will provide you with detailed info and the treatment process of TNBC.

What does it mean if cancer is considered triple-negative?

Triple-negative breast cancer or TNBC accounts for about ten to fifteen percent of all types of breast cancers. This unique term refers to the fact that the cancer cells do not have progesterone or estrogen receptors. Also, they do not make any of the proteins called HER2. This type of cancer is most commonly found in women of younger age, less than 40. Commonly they are Black or have a BRCA1 mutation.

TNBC is different from other types of invasive breast cancers. TNBC tends to grow and spread faster and it has fewer treatment options available with a worse outcome. So, it is recommended that you should have a check-up of your breast regularly to avoid this dangerous disease. For this, you should consult the best Cancer Doctor in Noida Dr. Manish Singhal, a renowned oncologist in Noida. 

What causes triple-negative cancer?

As research continues, many facts are being learned about the causes of triple-negative breast cancer specifically. Researchers do not exactly know the reasons behind TNBC, but they think that genetic mutation of BRCA1 might play a part. However, the BRCA1 gene is supposed to prevent cancer. But when it mutates, the gene reverses its course and makes the cells more vulnerable to cancer.

Another cause may be that it does not have any receptors. When these receptors are exposed to the corresponding hormones, they can stimulate cancer to grow. Some researchers believe that one possible cause of TNBC is the presence of a faulty BRCA1 gene. Some of the factors to support this theory are listed below:

• Every one of us inherits one set of BRCA1 genes from each of our parents.
• These genes help in preventing the development of cancer only when they function properly.
• A mutation in the BRCA1 gene is believed to make the body’s cells susceptible to further genetic alterations. This can lead to various forms of breast and ovarian cancer.
• Most of the breast cancers which are caused by a damaged BRCA1 gene are triple-negative.

Consulting a cancer Doctor in Noida like Dr. Manish Singhal would help you in getting the right form of diagnosis for the early detection of cancer. If it is detected then Dr. Manish Singhal, an Oncologist in Noida like him will provide you with the most advanced type of treatment for cancer for a timely recovery.

Is triple-negative cancer curable?

Metastatic cancer refers to a type of cancer that reoccurs distantly. It may be treatable but not curable. TNBC is a Metastatic type of cancer as it has a high recurrence rate within the first three years. Though there is a reduction in recurrence after five years. So, there are no post-therapy regimens.

People who get detected with an early-stage TNBC generally have to go through a shorter treatment course compared to other subtypes. But women with early-stage slow-growing estrogen receptor-positive cancers are often treated for many years.

There are few chances that treatment may make triple-negative breast cancer go away. It depends on the size of your tumor, and how far cancer has spread whether to the lymph nodes or other parts of your body. TNBC is the least common form of breast cancer which is the hardest to treat. But Dr. Manish Singhal, an Oncologist in Noida gives hope to his patients regarding TNBC with his latest medical technologies for treatment to provide healthier lives to his patients.

Is there a cure for triple-negative breast cancer?

Various types of medical treatments are being tested on triple-negative breast tumors in clinical trials. Such newer medicines called poly (ADP-ribose) polymerase inhibitors or PARP inhibitors have the potential to destroy cancer cells, and these drugs are now approved to treat triple-negative breast cancer. Another type of treatment called Immunotherapy helps your body to consider the malignant cells as harmful invaders so that your immune system can fight against the cancer cells.

Apart from this, Chemotherapy for TNBC can be intense as it shrinks the tumors and surgery can remove more of the tumor by taking away cancerous tissues. Radiation therapy uses beams of radiation to destroy cancer cells.

According to Dr. Manish Singhal, a renowned Oncologist in Noida, TNBC is aggressive cancer so the treatment should also be aggressive. TNBC is very sensitive to chemotherapy with some side effects but still an effective treatment to save lives. Dr. Manish Singhal, the Best Cancer Doctor in Noida always ensures personalized medical services with advanced treatment for patients with TNBC, from pre-checkups to post-treatment.